A Surfeit of Serpents
This curse comes from the baleful, ancient lore of Egypt. The sorcerer invokes the serpentine demons of Duat, the Egyptian underworld, and commands them to enter the belly of his enemy. Within an hour, the victim's stomach roils in pain. Nausea soon joins the pain, until at the end of the hour the victim vomits a living snake. The pain does not diminish for long, though. Soon the victim vomits another snake. His bowels heave, and he "excretes" snakes. The torment grows worse; he cannot void the snakes fast enough, and they chew their way out of his flesh, serpent after serpent, until he dies.
System: For each success the sorcerer's player rolls, the victim suffers two hours of the curse's effect. For the first two hours, as he voids snakes through his mouth and anus, the victim loses one health level of bashing damage per hour. Cainites can heal this damage normally. Each subsequent hour, however, the victim loses one health level of aggravated damage as the multiplying snakes chew out his insides. The victim can apply Fortitude against this damage for one hour per dot of Fortitude he possesses, but after that the damage becomes unsoakable. The damage is simply too great.
Cainites can heal the aggravated damage at the normal expenditure of blood and Willpower... and hope that neither runs out before the curse ends. A demon-snake's bite deals one level of aggravated damage but they are not poisonous. An hour after the curse ends, the snakes all vanish back to Duat.