Penrose, St. Louis

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St. Louis

Penrose is a neighborhood of St. Louis, Missouri. The neighborhood is located on the north side of the city just south of Interstate 70 and west of O’Fallon Park. It is bounded by Florissant Avenue and I-70 on the north, Natural Bridge on the south, North Newstead and Pope Avenue on the east, and Kingshighway Boulevard on the west.[2]